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The human evidence is weak and contested

Pathway analysis of proteins correlated to PTR highlighted not just STEAP3, but also metabolic enzymes involved in glycolysis (HK1, PFKM, PKLR, BSG essential for lactate transporter relocation to the membrane upon its synthesis 69 ), the pentose phosphate pathway (RPIA, G6PDX, PGLS, PGD, TALDO1, PRPS1), ferroptosis (STEAP3, GPX1, GPX4, HBB-y, NQO1, PRDX2, GSR, SOD3, CAT), all consistent with recent literature in humans 1217

doi: 10.1074/jbc.REV118.002804

These results were further confirmed by western blotting and immunofluorescence analyses showing strong nuclear translocation of YAP in HGC-27 cells treated with MV-carried OLFM4 (Fig